Dylan Thibault: Method to machine

Senior Biostatistician, Duke Clinical Research Institute

Durham, North Carolina.
Practicing since 2013.

I design the analysis. Trial endpoints, risk models, survival analysis, and the statistical analysis plans that fix every choice before the data arrive.

I build the software. Live calculators, AI systems for analysis plans and informed consent, and apps from my own studio.

I consult for clinical research teams on AI workflows, internal tools, and agent systems built for regulated work.

PlateMethod

Plate I: Hierarchical composite endpoints

When a trial has several outcomes of unequal weight, rank them. Compare every treated patient with every control on the gravest outcome first, and move down only on a tie. The win ratio is the wins divided by the losses.

SchematicIllustrative patients, not trial data

Fig. 1. Twelve treated patients (rows) against twelve controls (columns), each arm sorted worst to best, make 144 pairs. A pair is decided on the first rung where the two differ: death, then heart-failure hospitalization, then a symptom score, where a difference under 5 points is a tie. Everyone is followed for 12 months. Select a pair to read its ladder.

Machine

Hierarchical Endpoints Calculator

A public R Shiny app, hosted on shinyapps.io. The figure works through one illustrative trial by hand; the calculator does the same work for a real one.

Built with
R and Shiny
Status
Live and public
Hosted on
duke-som.shinyapps.io
Open the calculator

Schematic, not the system’s architectureWhat the calculator does

  1. Rank the outcomesThe gravest outcome sits on the top rung.
  2. Compare every pairEach treated patient against each control, rung by rung.
  3. Count wins, losses, and tiesThe win ratio, overall and within strata.

What it is for

  • Hierarchical and composite endpoints in clinical trials
  • Win-ratio methods
  • Stratified analyses
PlateMethod

Plate II: Risk prediction and calibration

A risk model is only as useful as its calibration. Sort patients by predicted risk, then check each group against what actually happened. A well-calibrated model sits on the diagonal.

SchematicIllustrative data

Fig. 2. Predicted against observed risk in ten groups of predicted risk, with 95% intervals. a, perfect calibration; b, a smoothed calibration curve; c, how the predicted risks are distributed. Point at a group, or focus the figure and use the arrow keys, to read it.

Machine

STS National Database risk models

From 2016 to 2021 I was lead statistician for the Society of Thoracic Surgeons (STS) National Database, across all three of its components: adult cardiac, general thoracic, and congenital heart surgery. The work produced more than 50 peer-reviewed papers.

Risk models among them: the 2021 adult cardiac models for multiple valve operations,1 a refined congenital heart surgery mortality model,2 and a new adult congenital mortality model.3

Where
Duke Clinical Research Institute
Status
Published

COVID Resource Calculator

A predictive calculator for hospital resource use during COVID-19: blood products, ventilation, length of stay, and readmission.

Where
Duke Clinical Research Institute
Status
Internal

Schematic, not the system’s architectureFour predictions

PlateMethod

Plate III: The statistical analysis plan

The protocol says what a trial will measure; the analysis plan says exactly how, before anyone sees the data. My first-author report for PCORI is on methods to improve comparative effectiveness analyses for COVID-19 treatments.4

SchematicA simplified map

Fig. 3. Which protocol sections inform which parts of a statistical analysis plan. Select a section on either side, or use the arrow keys, to trace its links. Drawn for illustration; it is not the tools’ internal model.

Machine

Automated SAP Generation

Upload a protocol and receive a tailored statistical analysis plan (SAP), ready to download. Built on retrieval-augmented generation (RAG) and a graph database.

Built with
Python, Next.js, a graph database, RAG
Status
Internal to DCRI

Agent-Based SAP Review

A command-line tool with two agents. One drafts the plan; the other reviews it against CRO and industry guidelines; the draft is revised and reviewed again.

Built with
A command-line interface and two agents
Status
Internal to DCRI

Schematic, not the system’s architectureThe review loop

PlateMethod

Plate IV: Informed consent quality

Consent is a conversation, and a conversation can be measured. Score each one on the same set of quality metrics, and every consent can be reviewed the same way.

SchematicOne illustrative conversation; metrics numbered, not named

Fig. 4. Schematic. Each conversation is scored on 17 quality metrics for regulatory review; the metric names are not shown.

Machine

AI Informed Consent Platform

A real-time, patient-facing chatbot for evaluating informed consent. Each conversation is scored on 17 quality metrics for regulatory review.

Built with
FastAPI and Next.js
Status
Internal to DCRI

What it does

  • Talks with the patient in real time, as the consent conversation happens.
  • Scores every conversation on the same 17 quality metrics.
  • Hands the scores to regulatory review.

One of the AI initiatives I lead at DCRI, alongside automated SAP generation and agent-based SAP review.

PlateMethod

Plate V: Time to event

Survival analysis asks how long until something happens, and counts everyone who leaves early until the moment they are censored. My papers include survival after deep brain stimulation,5 long-term outcomes after mitral valve surgery,6 and Medicare follow-up after esophageal cancer resection.7

SchematicIllustrative data

Fig. 5. Kaplan–Meier estimates for two arms of 30 patients, with the number still at risk below. a, a censored patient; b, median survival in the control arm. Drag across the plot, or focus it and use the arrow keys, to read survival at time t.

Machine

Mean Red Blood Cell Age Calculator

Red cells are a cohort too. The calculator turns N-15 isotope measurements, uploaded as patient CSV files, into mean red blood cell age, with plots and exports.

Built with
R and Shiny
Status
Live and public
Hosted on
duke-som.shinyapps.io
Open the calculator

Schematic: how survival defines mean age; not the calculator’s algorithm.

Mean age = ∫ t · S(t) dt∫ S(t) dt

In a steady-state population, the share of circulating cells aged t is proportional to S(t), the chance that a cell survives to age t.
PlateMethod

Plate VI: Reporting: the CONSORT flow

A trial report accounts for every patient, from enrollment to analysis. The habit travels. Here is my software studio, reported the same way: every product accounted for, by stage.

Schematic, after CONSORTStatus as of September 2026

Fig. 6. The five products of 5Tree LLC by stage, drawn as a CONSORT flow diagram. Every box is real; the figure is a joke only in its form.

Machine

TableSetter

The flagship. A family kitchen board: weekly meal plans, recipes, pantry and groceries, restaurant reservations, and an agent that drafts while the family approves every action.

Built with
SwiftUI, Next.js, Convex
Status
Beta
On the web
tablesetter.co

Stash

A hyperlocal marketplace for surplus food from nearby restaurants.

Status
In development
On the web
stashers.app

Fold-out

The record

Every paper indexed in PubMed with my name on it, placed at its date of publication. The median paper has eight authors: this is team science, and the statistics are my part of it.

Real dataCumulative papers indexed in PubMed, 2013 to 2026

Panel

Use the arrow keys to step through the papers; Page Up and Page Down move ten at a time.

The record. Each mark is one paper (N = 115) at its PubMed publication date; the curve steps up by one at each, in the manner of a Kaplan–Meier curve, and the rows below count papers by year. A, all papers. B, by journal field: cardiothoracic and vascular (53), neurology (37), and other (25). Ringed marks are the 3 first-author papers. Papers dated only by year sit at midyear. The + marks right-censoring: the current role is still in progress. Point at a mark, tap it, or focus the figure and use the arrow keys.

Source: 115 records from PubMed, retrieved 22 September 2026 with the query Dylan Thibault[Author]. Fields are assigned by journal.

Run the same search on PubMed
Table 1. Characteristics of the author (n = 1)
CharacteristicAuthor
Training and practice
Time in practice, y13
Degrees, No.3a
Programming languages, No.6b
Publications indexed in PubMedc
Papers, No.115
First author, No. (%)3(2.6)
Authors per paper, median (IQR)8(6–11)
Coauthors, approximate No.450d
Journals, No.59
Ann Thorac Surg, No. (%)29(25.2)
Recognition
DCRI Innovator Award, No.1e

Abbreviations: Ann Thorac Surg, The Annals of Thoracic Surgery; DCRI, Duke Clinical Research Institute; IQR, interquartile range.

a MS, biostatistics, Georgetown University; BS, biological sciences, and BA, philosophy, University of Vermont.

b R, SAS, Python, SQL, TypeScript, and Swift.

c Query Dylan Thibault[Author], 22 September 2026; includes 2 PCORI final research reports. Percentages use 115 as the denominator.

d 488 distinct name strings in the author lists, before variant spellings of the same person are merged.

e 2024, for ChatSum.

All 115 papers, newest firstEach links to PubMed
  1. 2026 1 paper

    1. Li M, Thibault DP, De Lott LB, Gravel CA, Freeman EE, Hamedani AG. Harmonization of self-reported and performance-based measures of vision using inverse probability weighting: an example using vision and depression in NHATS, CLSA, and LASI. J Gerontol A Biol Sci Med Sci. 2026. Author 2 of 6. PubMed
  2. 2025 6 papers

    1. Boutzoukas AE, Serrano PA, Cortez A, et al. Mpox epidemiology, barriers to treatment and prevention, and perceived stigma: a cross-sectional study. BMC Public Health. 2025. Author 5 of 8. PubMed
    2. Pham Nguyen TP, Thibault D, Gray SL, Weintraub D, Willis AW. Impact of Anticholinergic Burden and Clinical-Demographic Characteristics on Incident Dementia in Parkinson Disease. J Geriatr Psychiatry Neurol. 2025. Author 2 of 5. PubMed
    3. Vo AK, Crispo JAG, Liu LJW, et al. Examining the effects of race/ethnicity and other factors on outcomes of care for complex regional pain syndrome type 1 in the United States. PLOS Glob Public Health. 2025. Author 4 of 8. PubMed
    4. Hamedani AG, Thibault D, Rascovsky K, Willis AW, Langa KM. Comparing retrospective informant assessments to prospectively collected cognitive measures in the Health and Retirement Study. Alzheimers Dement (Amst). 2025. Author 2 of 5. PubMed
    5. Blasberg JD, Servais E, Thibault D, et al. Longitudinal Follow-up of Medicare Patients After Esophageal Cancer Resection in the STS Database. Ann Thorac Surg. 2025. Author 3 of 15. PubMed
    6. Hayanga HK, Rosenblum AJ, McGuire JA, et al. Undergraduate Students' Onlooker Response Prior to Arrival of Emergency Medical Services: An Assessment of Willingness to Respond. Disaster Med Public Health Prep. 2025. Author 5 of 12. PubMed
  3. 2024 8 papers

    1. Pham Nguyen TP, Thibault D, Hamedani AG, Willis AW. Attitudes and beliefs towards medication burden and deprescribing in Parkinson disease. BMC Neurol. 2024. Author 2 of 4. PubMed
    2. Hickman W, Dada RS, Thibault D, et al. Anesthetic Choice for Percutaneous Transcatheter Closure of the Left Atrial Appendage: A National Anesthesia Clinical Outcomes Registry Analysis. Ann Card Anaesth. 2024. Author 3 of 7. PubMed
    3. Rothenberg P, Lopez SJ, Thibault D, Pillai L, Minc SD. Predictors of Occlusion after Carotid Stenting. Ann Vasc Surg. 2024. Author 3 of 5. PubMed
    4. Dada RS, McGuire JA, Hayanga JWA, et al. Anesthetic Management for Ventricular Tachycardia Ablation: A National Anesthesia Clinical Outcomes Registry Analysis. J Cardiothorac Vasc Anesth. 2024. Author 4 of 7. PubMed
    5. Narayanaswami P, Sanders DB, Thomas L, et al. Comparative effectiveness of azathioprine and mycophenolate mofetil for myasthenia gravis (PROMISE-MG): a prospective cohort study. Lancet Neurol. 2024. Author 4 of 10. PubMed
    6. Thibault D, Thomas LE. Methods to Improve Comparative Effectiveness Analyses for COVID-19 Treatments. PCORI Final Research Report. 2024. First author. PubMed
    7. Miller JR, Hill KD, Thibault D, et al. Outcomes of the Kawashima: A Society of Thoracic Surgeons Congenital Heart Surgery Database Analysis. Ann Thorac Surg. 2024. Author 3 of 9. PubMed
    8. Worrell SG, Alvarado CE, Thibault D, et al. Impact of Diabetes on Pathologic Response to Multimodality Therapy for Esophageal Cancer. Ann Thorac Surg. 2024. Author 3 of 9. PubMed
  4. 2023 16 papers

    1. McGuire JA, Hayanga JWA, Thibault D, et al. Anesthetic Choice for Cardiovascular Implantable Electronic Device Placement and Lead Removal: A National Anesthesia Clinical Outcomes Registry Analysis. J Cardiothorac Vasc Anesth. 2023. Author 3 of 8. PubMed
    2. Schwann TA, Vekstein AM, Engelman DT, et al. Long-term Outcomes and Anticoagulation in Mitral Valve Surgery-A Report From The Society of Thoracic Surgeons Database. Ann Thorac Surg. 2023. Author 4 of 12. PubMed
    3. Foote HP, Thibault D, Gonzalez CD, et al. Center-level factors associated with shorter length of stay following stage 1 palliation: An analysis of the national pediatric cardiology quality improvement collaborative registry. Am Heart J. 2023. Author 2 of 9. PubMed
    4. Kakuturu J, Dhamija A, Chan E, et al. Mortality and cost of post-cardiotomy extracorporeal support in the United States. Perfusion. 2023. Author 5 of 7. PubMed
    5. Clarke NS, Thibault D, Alejo D, et al. Contemporary Patterns of Care in Tetralogy of Fallot: Analysis of The Society of Thoracic Surgeons Data. Ann Thorac Surg. 2023. Author 2 of 9. PubMed
    6. Nelson JS, Thibault D, O'Brien SM, et al. Development of a Novel Society of Thoracic Surgeons Adult Congenital Mortality Risk Model. Ann Thorac Surg. 2023. Author 2 of 13. PubMed
    7. Woods K, Minc SD, Thibault D, et al. Anesthetic choice for arteriovenous access creation: A National Anesthesia Clinical Outcomes Registry analysis. J Vasc Access. 2023. Author 3 of 9. PubMed
    8. Crispo JAG, Liu LJW, Noonan VK, et al. Nationwide emergency department visits for pediatric traumatic spinal cord injury in the United States, 2016-2020. Front Neurol. 2023. Author 7 of 9. PubMed
    9. Seese L, Chen EP, Badhwar V, et al. Optimal circulatory arrest temperature for aortic hemiarch replacement with antegrade brain perfusion. J Thorac Cardiovasc Surg. 2023. Author 4 of 18. PubMed
    10. Hamedani AG, Thibault D, Willis AW. Seasonal Variation in Neurologic Hospitalizations in the United States. Ann Neurol. 2023. Author 2 of 3. PubMed
    11. Mourad A, Thibault D, Holland TL, et al. Dexamethasone for Inpatients With COVID-19 in a National Cohort. JAMA Netw Open. 2023. Author 2 of 7. PubMed
    12. Khaitan PG, Vekstein AM, Thibault D, et al. Robotic Esophagectomy Trends and Early Surgical Outcomes: The US Experience. Ann Thorac Surg. 2023. Author 3 of 8. PubMed
    13. Abraham DS, Nguyen TPP, Blank LJ, et al. Channeling of New Neuropsychiatric Drugs-Impact on Safety and Effectiveness Studies. Neurotherapeutics. 2023. Author 4 of 9. PubMed
    14. Jawitz OK, Vekstein AM, Young R, et al. Comparing Consumer-Directed Hospital Rankings With STS Adult Cardiac Surgery Database Outcomes. Ann Thorac Surg. 2023. Author 6 of 12. PubMed
    15. Narayanaswami P, Sanders DB, Bibeau K, et al. Comparing Two Medicines for Adults with Myasthenia Gravis: The PROMISE-MG Study. PCORI Final Research Report. 2023. Author 7 of 12. PubMed
    16. Hayanga HK, Woods KE, Thibault DP, et al. Anesthetic management for transcatheter aortic valve replacement: A national anesthesia clinical outcomes registry analysis. Ann Card Anaesth. 2023. Author 3 of 9. PubMed
  5. 2022 16 papers

    1. Caceres Polo M, Thibault D, Jawitz OK, et al. Aortic Prosthetic Valve Endocarditis: Analysis of The Society of Thoracic Surgeons Database. Ann Thorac Surg. 2022. Author 2 of 8. PubMed
    2. Chew JD, Hill KD, Soslow JH, et al. Congenitally Corrected Transposition Cardiac Surgery: Society of Thoracic Surgeons Database Analysis. Ann Thorac Surg. 2022. Author 7 of 10. PubMed
    3. Woods K, Hayanga JWA, Cannon J, et al. Staffing in a Level 1 Trauma Center: Quantifying Capacity for Preparedness. Disaster Med Public Health Prep. 2022. Author 10 of 13. PubMed
    4. Thourani VH, Brennan JM, Edelman JJ, et al. Association of Volume and Outcomes in 234 556 Patients Undergoing Surgical Aortic Valve Replacement. Ann Thorac Surg. 2022. Author 4 of 36. PubMed
    5. Pham Nguyen TP, Thibault D, Hamedani AG, Weintraub D, Willis AW. Atypical antipsychotic use and mortality risk in Parkinson disease. Parkinsonism Relat Disord. 2022. Author 2 of 5. PubMed
    6. Liu LJW, Crispo JAG, Bach P, et al. Amphetamine-related care in the USA, 2003-2014: cross-sectional analyses examining inpatient trends and factors associated with hospitalisation outcomes. BMJ Open. 2022. Author 5 of 7. PubMed
    7. Seese L, Turbendian HK, Thibault D, et al. Utilization and Outcomes of the Nikaidoh, Rastelli, and REV Procedures: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database. Ann Thorac Surg. 2022. Author 3 of 12. PubMed
    8. Servais EL, Miller DL, Thibault D, et al. Conversion to Thoracotomy During Thoracoscopic vs Robotic Lobectomy: Predictors and Outcomes. Ann Thorac Surg. 2022. Author 3 of 10. PubMed
    9. Dhamija A, Thibault D, Fugett J, et al. Incremental effect of complications on mortality and hospital costs in adult ECMO patients. Perfusion. 2022. Author 2 of 7. PubMed
    10. Jawitz OK, Lawton JS, Thibault D, et al. Sex Differences in Coronary Artery Bypass Grafting Techniques: A Society of Thoracic Surgeons Database Analysis. Ann Thorac Surg. 2022. Author 3 of 9. PubMed
    11. Kelly DJ, Thibault D, Tam D, et al. Readmission Following Hospitalization for Traumatic Brain Injury: A Nationwide Study. J Head Trauma Rehabil. 2022. Author 2 of 7. PubMed
    12. Minc SD, Thibault D, Marone L. Outcomes of carotid artery stenting in patients with radiation arteritis compared with those with atherosclerotic disease. J Vasc Surg. 2022. Author 2 of 3. PubMed
    13. Decker BM, Thibault D, Davis KA, Willis AW. Population-Based Study of Nonelective Postpartum Readmissions in Women With Stroke, Migraine, Multiple Sclerosis, and Myasthenia Gravis. Neurology. 2022. Author 2 of 4. PubMed
    14. Pasquali SK, Thibault D, Hall M, et al. Evolving Cost-Quality Relationship in Pediatric Heart Surgery. Ann Thorac Surg. 2022. Author 2 of 16. PubMed
    15. Jacobs JP, Shahian DM, Badhwar V, et al. The Society of Thoracic Surgeons 2021 Adult Cardiac Surgery Risk Models for Multiple Valve Operations. Ann Thorac Surg. 2022. Author 4 of 17. PubMed
    16. Crispo JAG, Liu LJW, Noonan VK, et al. Pediatric Traumatic Spinal Cord Injury in the United States: A National Inpatient Analysis. Top Spinal Cord Inj Rehabil. 2022. Author 7 of 9. PubMed
  6. 2021 18 papers

    1. Hamedani AG, Blank L, Thibault DP, Willis AW. Impact of ICD-9 to ICD-10 Coding Transition on Prevalence Trends in Neurology. Neurol Clin Pract. 2021. Author 3 of 4. PubMed
    2. Dada RS, Hayanga JWA, Woods K, et al. Anesthetic Choice for Atrial Fibrillation Ablation: A National Anesthesia Clinical Outcomes Registry Analysis. J Cardiothorac Vasc Anesth. 2021. Author 5 of 10. PubMed
    3. Danielle Minc S, Budi S, Thibault D, et al. Opportunities for diabetes and peripheral artery disease-related lower limb amputation prevention in an Appalachian state: A longitudinal analysis. Prev Med Rep. 2021. Author 3 of 7. PubMed
    4. Serfas JD, Thibault D, Andersen ND, et al. The Evolving Surgical Burden of Fontan Failure: An Analysis of The Society of Thoracic Surgeons Congenital Heart Surgery Database. Ann Thorac Surg. 2021. Author 2 of 10. PubMed
    5. Fraser CD 3rd, Ravekes W, Thibault D, et al. Diaphragm Paralysis After Pediatric Cardiac Surgery: An STS Congenital Heart Surgery Database Study. Ann Thorac Surg. 2021. Author 3 of 12. PubMed
    6. Minc SD, Hayanga HK, Thibault D, et al. Vascular Complications Increase Hospital Charges and Mortality in Adult Patients on Extracorporeal Membrane Oxygenation in the United States. Semin Thorac Cardiovasc Surg. 2021. Author 3 of 7. PubMed
    7. Towe CW, Thibault DP, Worrell SG, et al. Factors Associated With Successful Postoperative Day One Discharge After Anatomic Lung Resection. Ann Thorac Surg. 2021. Author 2 of 7. PubMed
    8. Pham Nguyen TP, Jacobs D, Thibault D, Willis AW. Multiple sclerosis hospitalizations among users of oral disease-modifying therapies. Mult Scler Relat Disord. 2021. Author 3 of 4. PubMed
    9. Metkus TS, Thibault D, Grant MC, et al. Transesophageal Echocardiography in Patients Undergoing Coronary Artery Bypass Graft Surgery. J Am Coll Cardiol. 2021. Author 2 of 11. PubMed
    10. Brown LM, Thibault DP, Kosinski AS, et al. Readmission After Lobectomy for Lung Cancer: Not All Complications Contribute Equally. Ann Surg. 2021. Author 2 of 7. PubMed
    11. Pham Nguyen TP, Abraham DS, Thibault D, Weintraub D, Willis AW. Low continuation of antipsychotic therapy in Parkinson disease - intolerance, ineffectiveness, or inertia? BMC Neurol. 2021. Author 3 of 5. PubMed
    12. Jawitz OK, Raman V, Thibault D, et al. Complications after Ravitch versus Nuss repair of pectus excavatum: A Society of Thoracic Surgeons (STS) General Thoracic Surgery Database analysis. Surgery. 2021. Author 3 of 8. PubMed
    13. Aamodt WW, Travers J, Thibault D, Willis AW. Hospital Magnet Status Associates With Inpatient Safety in Parkinson Disease. J Neurosci Nurs. 2021. Author 3 of 4. PubMed
    14. Crispo JAG, Lam M, Le B, et al. Survival and Health Care Use After Deep Brain Stimulation for Parkinson's Disease. Can J Neurol Sci. 2021. Author 8 of 11. PubMed
    15. Decker BM, Thibault D, Davis KA, Willis AW. A nationwide analysis of maternal morbidity and acute postpartum readmissions in women with epilepsy. Epilepsy Behav. 2021. Author 2 of 4. PubMed
    16. Riggs KW, Zafar F, Jacobs ML, et al. Tracheal surgery for airway anomalies associated with increased mortality in pediatric patients undergoing heart surgery: Society of Thoracic Surgeons Database analysis. J Thorac Cardiovasc Surg. 2021. Author 5 of 12. PubMed
    17. Jacobs ML, Jacobs JP, Thibault D, et al. Updating an Empirically Based Tool for Analyzing Congenital Heart Surgery Mortality. World J Pediatr Congenit Heart Surg. 2021. Author 3 of 16. PubMed
    18. Blank LJ, Acton EK, Thibault D, Willis AW. Neurodegenerative disease is associated with increased incidence of epilepsy: a population based study of older adults. Age Ageing. 2021. Author 3 of 4. PubMed
  7. 2020 18 papers

    1. Hamedani AG, Thibault DP, Revere KE, et al. Trends in the Surgical Treatment of Pseudotumor Cerebri Syndrome in the United States. JAMA Netw Open. 2020. Author 2 of 7. PubMed
    2. Pham Nguyen TP, Chen Y, Thibault D, Leonard CE, Hennessy S, Willis A. Does hospitalization for thromboembolism improve oral anticoagulant adherence in patients with atrial fibrillation? J Am Pharm Assoc (2003). 2020. Author 3 of 6. PubMed
    3. Pham Nguyen TP, Chen Y, Thibault D, Leonard CE, Hennessy S, Willis A. Impact of Hospitalization and Medication Switching on Post-discharge Adherence to Oral Anticoagulants in Patients With Atrial Fibrillation. Pharmacotherapy. 2020. Author 3 of 6. PubMed
    4. Pasquali SK, Thibault D, O'Brien SM, et al. National Variation in Congenital Heart Surgery Outcomes. Circulation. 2020. Author 2 of 12. PubMed
    5. Minc SD, Goodney PP, Misra R, Thibault D, Smith GS, Marone L. The effect of rurality on the risk of primary amputation is amplified by race. J Vasc Surg. 2020. Author 4 of 6. PubMed
    6. Pasquali SK, Chiswell K, Hall M, et al. Estimating Resource Utilization in Congenital Heart Surgery. Ann Thorac Surg. 2020. Author 4 of 17. PubMed
    7. Hamedani AG, Thibault DP, Shea JA, Willis AW. Self-reported vision and hallucinations in older adults: results from two longitudinal US health surveys. Age Ageing. 2020. Author 2 of 4. PubMed
    8. Mehaffey JH, Hawkins RB, Charles EJ, et al. Distressed communities are associated with worse outcomes after coronary artery bypass surgery. J Thorac Cardiovasc Surg. 2020. Author 4 of 9. PubMed
    9. Zheng R, Rios-Diaz AJ, Thibault DP, Crispo JAG, Willis AW, Willis AI. A contemporary analysis of goiters undergoing surgery in the United States. Am J Surg. 2020. Author 3 of 6. PubMed
    10. Ellis DE, Zaoutis T, Thibault DP, Crispo JAG, Abraham DS, Willis AW. Readmissions after hospital care for meningitis in the United States. Am J Infect Control. 2020. Author 3 of 6. PubMed
    11. Kessler SK, Blank LJ, Glusman J, et al. Unplanned Readmissions of Children With Epilepsy in the United States. Pediatr Neurol. 2020. Author 4 of 9. PubMed
    12. Fullard M, Thibault D, Zisling H, Crispo JA, Willis A. Parkinson Disease Associated Differences in Elective Orthopedic Surgery Outcomes: A National Readmissions Database Analysis. J Parkinsons Dis. 2020. Author 2 of 5. PubMed
    13. Hamedani AG, Pauly M, Thibault DP, Gonzalez-Alegre P, Willis AW. Inpatient gastrostomy in Huntington's disease: Nationwide analysis of utilization and outcomes compared to amyotrophic lateral sclerosis. Clin Park Relat Disord. 2020. Author 3 of 5. PubMed
    14. Mendizabal A, Thibault DP, Crispo JA, Paley A, Willis AW. Comorbid disease drives short-term hospitalization outcomes in patients with multiple sclerosis. Neurol Clin Pract. 2020. Author 2 of 5. PubMed
    15. Minc SD, Hendricks B, Misra R, et al. Geographic variation in amputation rates among patients with diabetes and/or peripheral arterial disease in the rural state of West Virginia identifies areas for improved care. J Vasc Surg. 2020. Author 5 of 7. PubMed
    16. Caceres Polo M, Thibault D, Thourani VH, Badhwar V, Xian Y, Shemin RJ. Risk Analysis and Outcomes of Postoperative Renal Failure After Aortic Valve Surgery in the United States. Ann Thorac Surg. 2020. Author 2 of 6. PubMed
    17. Jawitz OK, Gulack BC, Brennan JM, et al. Association of postoperative complications and outcomes following coronary artery bypass grafting. Am Heart J. 2020. Author 4 of 9. PubMed
    18. Schneider RB, Jimenez-Shahed J, Abraham DS, et al. Acute readmission following deep brain stimulation surgery for Parkinson's disease: A nationwide analysis. Parkinsonism Relat Disord. 2020. Author 4 of 20. PubMed
  8. 2019 12 papers

    1. Chew JD, Hill KD, Jacobs ML, et al. Congenital Heart Surgery Outcomes in Turner Syndrome: The Society of Thoracic Surgeons Database Analysis. Ann Thorac Surg. 2019. Author 8 of 11. PubMed
    2. Greene NH, Jooste EH, Thibault DP, et al. A Study of Practice Behavior for Endotracheal Intubation Site for Children With Congenital Heart Disease Undergoing Surgery: Impact of Endotracheal Intubation Site on Perioperative Outcomes-An Analysis of the Society of Thoracic Surgeons Congenital Cardiac Anesthesia Society Database. Anesth Analg. 2019. Author 3 of 11. PubMed
    3. Jacobs JP, O'Brien SM, Hill KD, et al. Refining The Society of Thoracic Surgeons Congenital Heart Surgery Database Mortality Risk Model With Enhanced Risk Adjustment for Chromosomal Abnormalities, Syndromes, and Noncardiac Congenital Anatomic Abnormalities. Ann Thorac Surg. 2019. Author 13 of 16. PubMed
    4. Crispo JAG, Thibault DP, Willis AW. Adverse Drug Events as a Reason for Adult Hospitalization: A Nationwide Readmission Study. Ann Pharmacother. 2019. Author 2 of 3. PubMed
    5. Thibault D, Wallace AS, Jacobs ML, et al. Postoperative Transcatheter Interventions in Children Undergoing Congenital Heart Surgery. Circ Cardiovasc Interv. 2019. First author. PubMed
    6. Wallen T, Habertheuer A, Bavaria JE, et al. Elective Aortic Root Replacement in North America: Analysis of STS Adult Cardiac Surgery Database. Ann Thorac Surg. 2019. Author 8 of 13. PubMed
    7. Kilic A, Acker MA, Gleason TG, et al. Clinical Outcomes of Mitral Valve Reoperations in the United States: An Analysis of The Society of Thoracic Surgeons National Database. Ann Thorac Surg. 2019. Author 6 of 10. PubMed
    8. Wei LM, Thibault DP, Rankin JS, et al. Contemporary Surgical Management of Hypertrophic Cardiomyopathy in the United States. Ann Thorac Surg. 2019. Author 2 of 16. PubMed
    9. Rios-Diaz AJ, Zheng R, Thibault DP, Crispo JAG, Willis AW, Willis AI. Understanding nationwide readmissions after thyroid surgery. Surgery. 2019. Author 3 of 6. PubMed
    10. Recober A, Patel PB, Thibault DP, Hill AW, Kaiser EA, Willis AW. Sociodemographic Factors Associated With Hospital Care for Pediatric Migraine: A National Study Using the Kids' Inpatient Dataset. Pediatr Neurol. 2019. Author 3 of 6. PubMed
    11. Blank LJ, Crispo JAG, Thibault DP, Davis KA, Litt B, Willis AW. Readmission after seizure discharge in a nationally representative sample. Neurology. 2019. Author 3 of 6. PubMed
    12. Hill CE, Blank LJ, Thibault D, et al. Continuous EEG is associated with favorable hospitalization outcomes for critically ill patients. Neurology. 2019. Author 3 of 7. PubMed
  9. 2018 9 papers

    1. Crispo JAG, Thibault DP, Fortin Y, Krewski D, Willis AW. Association between medication-related adverse events and non-elective readmission in acute ischemic stroke. BMC Neurol. 2018. Author 2 of 5. PubMed
    2. Likosky DS, Harrington SD, Cabrera L, et al. Collaborative Quality Improvement Reduces Postoperative Pneumonia After Isolated Coronary Artery Bypass Grafting Surgery. Circ Cardiovasc Qual Outcomes. 2018. Author 7 of 11. PubMed
    3. Ramchand P, Thibault DP, Crispo JA, et al. Readmissions After Mechanical Thrombectomy for Acute Ischemic Stroke in the United States: A Nationwide Analysis. J Stroke Cerebrovasc Dis. 2018. Author 2 of 8. PubMed
    4. Cox ML, Gulack BC, Thibault DP, et al. Outcomes after coronary artery bypass grafting in patients with myocardial infarction, cardiogenic shock and unresponsive neurological state: analysis of the Society of Thoracic Surgeons Database. Eur J Cardiothorac Surg. 2018. Author 3 of 10. PubMed
    5. Holst KA, Dearani JA, Said SM, et al. Surgical Management and Outcomes of Ebstein Anomaly in Neonates and Infants: A Society of Thoracic Surgeons Congenital Heart Surgery Database Analysis. Ann Thorac Surg. 2018. Author 11 of 16. PubMed
    6. Gammie JS, Chikwe J, Badhwar V, et al. Isolated Mitral Valve Surgery: The Society of Thoracic Surgeons Adult Cardiac Surgery Database Analysis. Ann Thorac Surg. 2018. Author 4 of 17. PubMed
    7. Fallon JM, DeSimone JP, Brennan JM, et al. The Incidence and Consequence of Prosthesis-Patient Mismatch After Surgical Aortic Valve Replacement. Ann Thorac Surg. 2018. Author 5 of 9. PubMed
    8. Crispo JAG, Thibault DP, Fortin Y, Willis AW. Inpatient care for stiff person syndrome in the United States: a nationwide readmission study. J Clin Mov Disord. 2018. Author 2 of 4. PubMed
    9. Fullard ME, Thibault DP, Todaro V, et al. Sex disparities in health and health care utilization after Parkinson diagnosis: Rethinking PD associated disability. Parkinsonism Relat Disord. 2018. Author 2 of 12. PubMed
  10. 2017 3 papers

    1. Mendizabal A, Ngo Vu AT, Thibault D, Gonzalez-Alegre P, Willis A. Hospitalizations of Children with Huntington's Disease in the United States. Mov Disord Clin Pract. 2017. Author 3 of 5. PubMed
    2. Fullard ME, Thibault DP, Hill A, et al. Utilization of rehabilitation therapy services in Parkinson disease in the United States. Neurology. 2017. Author 2 of 17. PubMed
    3. Gonzales S, Mullen MT, Skolarus L, Thibault DP, Udoeyo U, Willis AW. Progressive rural-urban disparity in acute stroke care. Neurology. 2017. Author 4 of 6. PubMed
  11. 2016 6 papers

    1. Willis AW, Thibault DP, Schmidt PN, Dorsey ER, Weintraub D. Hospital care for mental health and substance abuse conditions in Parkinson's disease. Mov Disord. 2016. Author 2 of 5. PubMed
    2. Mendizabal A, Thibault DP, Willis AW. Patient safety events in hospital care of individuals with epilepsy. Epilepsia. 2016. Author 2 of 3. PubMed
    3. Crispo JA, Willis AW, Thibault DP, et al. Associations between Anticholinergic Burden and Adverse Health Outcomes in Parkinson Disease. PLoS One. 2016. Author 3 of 11. PubMed
    4. Crispo JAG, Willis AW, Thibault DP, et al. Associations Between Cardiovascular Events and Nonergot Dopamine Agonists in Parkinson's Disease. Mov Disord Clin Pract. 2016. Author 3 of 10. PubMed
    5. Moten AS, Thibault DP, Willis AW, Willis AI. Demographics, disparities, and outcomes in substernal goiters in the United States. Am J Surg. 2016. Author 2 of 4. PubMed
    6. Thibault DP, Mendizabal A, Abend NS, Davis KA, Crispo J, Willis AW. Hospital care for mental health and substance abuse in children with epilepsy. Epilepsy Behav. 2016. First author. PubMed
  12. 2015 2 papers

    1. Crispo JA, Fortin Y, Thibault DP, et al. Trends in inpatient antiparkinson drug use in the USA, 2001-2012. Eur J Clin Pharmacol. 2015. Author 3 of 10. PubMed
    2. Safarpour D, Thibault DP, DeSanto CL, et al. Nursing home and end-of-life care in Parkinson disease. Neurology. 2015. Author 2 of 7. PubMed

Other instruments

Work without a plate of its own: a meeting summarizer and open-source tools.

WorkWhat it doesBuilt withStatus
ChatSumSummarizes meeting minutes. DCRI Innovator Award, 2024.GPT-4oInternal
walmart-pp-cliAn agent-native grocery command line.GoOn GitHub
CLI Printing PressUpstream work on OpenTable and Tock reservations.GoPull requests on GitHub
duke-ml-2026-chatbotsA Duke ML tutorial: chatbots on Azure AI Foundry.Python, TypeScriptOn GitHub
unpluginFinds and removes audio plugins on macOS.PythonOn GitHub
gemini-imageAn OpenClaw skill and command line for Gemini images.PythonOn GitHub
cowork-job-searchA local-first Claude Cowork workspace.Claude CoworkOn GitHub

Consulting

For pharma, CROs, health systems, and academic groups that want the statistics and the software from the same person.

  • AI strategy and workflow designWhere AI belongs in a research workflow, and where a person stays in the loop.
  • Custom internal toolsCalculators, review tools, and dashboards built around one team’s data and decisions.
  • Agent and RAG systemsRetrieval and multi-agent systems for regulated or research-heavy work.
  • Team trainingHands-on AI training for statisticians and research staff.

Best fit

Teams that need both domain judgment and execution: someone who can read the protocol and ship the tool.

Typical outcomes

A clear map of the workflow, a scoped concept for a tool, an implementation plan, or a shipped prototype.

Start a conversation

Correspondence

Tell me about the study, the workflow, or the tool you have in mind.

Elsewhere