Hierarchical Endpoints Calculator
A public R Shiny app, hosted on shinyapps.io. The figure works through one illustrative trial by hand; the calculator does the same work for a real one.
Open the calculatorSchematic, not the system’s architectureWhat the calculator does
- Rank the outcomesThe gravest outcome sits on the top rung.
- Compare every pairEach treated patient against each control, rung by rung.
- Count wins, losses, and tiesThe win ratio, overall and within strata.
What it is for
- Hierarchical and composite endpoints in clinical trials
- Win-ratio methods
- Stratified analyses